Title : Aspirin treatment hampers the use of plasma microRNA-126 as a biomarker for the progression of vascular disease.

Pub. Date : 2013 Nov

PMID : 23386708






3 Functional Relationships(s)
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1 METHODS AND RESULTS: In vitro platelet activation resulted in the transfer of miR-126 from the platelet to the plasma compartment, which was prevented by aspirin. Aspirin microRNA 126 Homo sapiens
2 The administration of aspirin resulted both in platelet inhibition and concomitantly reduced circulating levels of platelet-derived microRNAs including miR-126. Aspirin microRNA 126 Homo sapiens
3 Consequently, in patho-physiological conditions associated with platelet activation, such as diabetes type 2, the administration of aspirin may lead to reduced levels of circulating miR-126. Aspirin microRNA 126 Homo sapiens