Title : Activation of AMP-activated protein kinase by a plant-derived dihydroisosteviol in human intestinal epithelial cell.

Pub. Date : 2013

PMID : 23343619






1 Functional Relationships(s)
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1 Our previous study has shown that dihydroisosteviol (DHIS), a derivative of stevioside isolated from Stevia rebaudiana (Bertoni), inhibits cystic fibrosis transmembrane conductance regulator (CFTR)-mediated transepithelial chloride secretion across monolayers of human intestinal epithelial (T84) cells and prevents cholera toxin-induced intestinal fluid secretion in mouse closed loop models. stevioside CF transmembrane conductance regulator Homo sapiens