Pub. Date : 2012 Aug 17
PMID : 22767592
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, human SIRT5 (sirtuin 5), which has been reported to exhibit little deacetylase activity, was recently identified as an NAD-dependent demalonylase and desuccinylase. | NAD | sirtuin 5 | Homo sapiens |
| 2 | However, human SIRT5 (sirtuin 5), which has been reported to exhibit little deacetylase activity, was recently identified as an NAD-dependent demalonylase and desuccinylase. | NAD | sirtuin 5 | Homo sapiens |
| 3 | Previously, we solved the crystal structure of a SIRT5-succinyl-lysine peptide-NAD complex. | succinyl-lysine peptide | sirtuin 5 | Homo sapiens |
| 4 | Previously, we solved the crystal structure of a SIRT5-succinyl-lysine peptide-NAD complex. | NAD | sirtuin 5 | Homo sapiens |
| 5 | Here, we present two more structures: a binary complex of SIRT5 with an H3K9 succinyl peptide and a binary complex of SIRT5 with a bicyclic intermediate obtained by incubating SIRT5-H3K9 thiosuccinyl peptide co-crystals with NAD. | thiosuccinyl peptide | sirtuin 5 | Homo sapiens |
| 6 | Here, we present two more structures: a binary complex of SIRT5 with an H3K9 succinyl peptide and a binary complex of SIRT5 with a bicyclic intermediate obtained by incubating SIRT5-H3K9 thiosuccinyl peptide co-crystals with NAD. | thiosuccinyl peptide | sirtuin 5 | Homo sapiens |
| 7 | Here, we present two more structures: a binary complex of SIRT5 with an H3K9 succinyl peptide and a binary complex of SIRT5 with a bicyclic intermediate obtained by incubating SIRT5-H3K9 thiosuccinyl peptide co-crystals with NAD. | NAD | sirtuin 5 | Homo sapiens |
| 8 | Here, we present two more structures: a binary complex of SIRT5 with an H3K9 succinyl peptide and a binary complex of SIRT5 with a bicyclic intermediate obtained by incubating SIRT5-H3K9 thiosuccinyl peptide co-crystals with NAD. | NAD | sirtuin 5 | Homo sapiens |