Title : ApoE promotes hepatic selective uptake but not RCT due to increased ABCA1-mediated cholesterol efflux to plasma.

Pub. Date : 2012 May

PMID : 22383685






1 Functional Relationships(s)
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1 However, blocking ABCA1-mediated cholesterol efflux from hepatocytes in AdhApoE3-injected mice using probucol increased biliary cholesterol secretion (P < 0.05), fecal neutral sterol excretion (P < 0.05), and in vivo RCT (P < 0.01), specifically within neutral sterols. Probucol ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus