Title : Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.

Pub. Date : 2012 Jan 6

PMID : 22084242






2 Functional Relationships(s)
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1 Notably, P-TEFb complexes associated with short BRD4 contain HEXIM1 and 7SK snRNA, implicating the PID in the liberation of P-TEFb from the 7SK small nuclear ribonucleoprotein complex (7SK snPNP). (2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid bromodomain containing 4 Homo sapiens
2 Notably, P-TEFb complexes associated with short BRD4 contain HEXIM1 and 7SK snRNA, implicating the PID in the liberation of P-TEFb from the 7SK small nuclear ribonucleoprotein complex (7SK snPNP). (2s)-Tert-Butoxy[3-(3,4-Dihydro-2h-1-Benzopyran-6-Yl)-1-Methyl-1h-Indol-2-Yl]acetic Acid bromodomain containing 4 Homo sapiens