Pub. Date : 2011 Nov 11
PMID : 22076378
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase. | NAD | sirtuin 5 | Homo sapiens |
| 2 | The preference for succinyl and malonyl groups was explained by the presence of an arginine residue (Arg(105)) and tyrosine residue (Tyr(102)) in the acyl pocket of Sirt5. | Arginine | sirtuin 5 | Homo sapiens |
| 3 | The preference for succinyl and malonyl groups was explained by the presence of an arginine residue (Arg(105)) and tyrosine residue (Tyr(102)) in the acyl pocket of Sirt5. | Arginine | sirtuin 5 | Homo sapiens |
| 4 | The preference for succinyl and malonyl groups was explained by the presence of an arginine residue (Arg(105)) and tyrosine residue (Tyr(102)) in the acyl pocket of Sirt5. | Tyrosine | sirtuin 5 | Homo sapiens |
| 5 | The preference for succinyl and malonyl groups was explained by the presence of an arginine residue (Arg(105)) and tyrosine residue (Tyr(102)) in the acyl pocket of Sirt5. | Tyrosine | sirtuin 5 | Homo sapiens |
| 6 | Thus, protein lysine succinylation may represent a posttranslational modification that can be reversed by Sirt5 in vivo. | Lysine | sirtuin 5 | Homo sapiens |