Pub. Date : 2012 Jan
PMID : 21962538
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro. | alpha-hexachlorocyclohexane | androgen receptor | Homo sapiens |
| 2 | Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro. | alpha-hexachlorocyclohexane | androgen receptor | Homo sapiens |
| 3 | There was no direct effect of alpha-HCH on AR but both isomers significantly suppressed the activity of AR in co-exposure with the natural ligand dihydrotestosterone in a concentration-dependent manner. | alpha-hexachlorocyclohexane | androgen receptor | Homo sapiens |
| 4 | Although studies with other pesticides demonstrated strong enantioselective differences in toxicity, the present research shows rather minor differences in modulations of AR by both alpha-HCH enantiomers. | alpha-hexachlorocyclohexane | androgen receptor | Homo sapiens |
| 5 | For the first time, enantioselective effects of alpha-HCH were demonstrated and the results suggest interaction with multiple regulatory events controlling the AR activity. | alpha-hexachlorocyclohexane | androgen receptor | Homo sapiens |