Pub. Date : 2011 Dec
PMID : 21890894
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, by analyzing the dynamics of Brd4 during ultraviolet or hexamethylene bisacetamide treatment, we show that the signal-induced release of chromatin-bound Brd4 is essential for its functional transition. | hexamethylene bisacetamide | bromodomain containing 4 | Homo sapiens |
2 | Here, by analyzing the dynamics of Brd4 during ultraviolet or hexamethylene bisacetamide treatment, we show that the signal-induced release of chromatin-bound Brd4 is essential for its functional transition. | hexamethylene bisacetamide | bromodomain containing 4 | Homo sapiens |
3 | Upon treatment, Brd4 is released from chromatin, mostly due to signal-triggered deacetylation of nucleosomal histone H4 at acetylated-lysine 5/8 (H4K5ac/K8ac). | acetylated-lysine | bromodomain containing 4 | Homo sapiens |