Title : Hydroxyl radical production by free and DNA-bound aminoquinone antibiotics and its role in DNA degradation. Electron spin resonance detection of hydroxyl radicals by spin trapping.

Pub. Date : 1978 Nov

PMID : 216472






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Incubation of the semiquinone from mitomycin C, mitomycin B, or streptonigrin (SN) with catalase or with superoxide dismutase inhibits the generation of OH, implying the intermediacy of H2O2 and O2 in its formation. Mitomycin catalase Homo sapiens