Pub. Date : 1990
PMID : 2154654
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Binding of the radiolabeled platelet-activating-factor (PAF) receptor antagonist RP52770, [( 3H]-N-(3-chlorophenyl)-3-(3-pyridinyl)-1H, 3H-pyrrolo- [1,2-c]thiazole-7-carboxamide) to receptors in human lung membranes was time- dependent, protein-dependent, reversible and saturable. | [( 3h]-n-(3-chlorophenyl)-3-(3-pyridinyl)-1h | platelet activating factor receptor | Homo sapiens |
2 | Binding of the radiolabeled platelet-activating-factor (PAF) receptor antagonist RP52770, [( 3H]-N-(3-chlorophenyl)-3-(3-pyridinyl)-1H, 3H-pyrrolo- [1,2-c]thiazole-7-carboxamide) to receptors in human lung membranes was time- dependent, protein-dependent, reversible and saturable. | 3h-pyrrolo- [1,2-c]thiazole-7-carboxamide | platelet activating factor receptor | Homo sapiens |
3 | [3H]-RP52770 binding to the PAF receptor was competitively displaced by PAF and receptor antagonists. | Tritium | platelet activating factor receptor | Homo sapiens |
4 | These results clearly demonstrate that cations and guanine nucleotide can regulate the affinity states of the PAF receptor in human lung membranes. | Guanine Nucleotides | platelet activating factor receptor | Homo sapiens |