Pub. Date : 1990
PMID : 2134892
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These effects of TGF-beta 1 are not mediated by endogenous production of prostaglandin, since the basal level of prostaglandin E2 was very low and rather inhibited by TGF-beta 1; and, further, indomethacin did not modify the effects of TGF-beta 1 on the cells under the present conditions. | Dinoprostone | transforming growth factor, beta 1 | Mus musculus |
| 2 | These effects of TGF-beta 1 are not mediated by endogenous production of prostaglandin, since the basal level of prostaglandin E2 was very low and rather inhibited by TGF-beta 1; and, further, indomethacin did not modify the effects of TGF-beta 1 on the cells under the present conditions. | Indomethacin | transforming growth factor, beta 1 | Mus musculus |
| 3 | Hydroxyurea completely blocked the stimulation of DNA synthesis by TGF-beta 1, but partially inhibited the collagen synthesis, suggesting that the TGF-beta 1-stimulated collagen synthesis is at least in part linked to the proliferation. | Hydroxyurea | transforming growth factor, beta 1 | Mus musculus |
| 4 | Hydroxyurea completely blocked the stimulation of DNA synthesis by TGF-beta 1, but partially inhibited the collagen synthesis, suggesting that the TGF-beta 1-stimulated collagen synthesis is at least in part linked to the proliferation. | Hydroxyurea | transforming growth factor, beta 1 | Mus musculus |
| 5 | However, the stimulation of collagen synthesis by TGF-beta 1 was greater than that of DNA synthesis, and further, the amount of hydroxyproline in the cell was evidently augmented by TGF-beta 1. | Hydroxyproline | transforming growth factor, beta 1 | Mus musculus |
| 6 | However, the stimulation of collagen synthesis by TGF-beta 1 was greater than that of DNA synthesis, and further, the amount of hydroxyproline in the cell was evidently augmented by TGF-beta 1. | Hydroxyproline | transforming growth factor, beta 1 | Mus musculus |