Title : BMP-Id pathway targeted by cholesterol myristate suppresses the apoptosis of PC12 cells.

Pub. Date : 2011 Jan 7

PMID : 20970407






2 Functional Relationships(s)
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1 PC12 cells transfected by the inhibitor of differentiation (Id1) promoter reporter construct target gene of BMP4 signaling; cholesterol myristate increases the activity of Id1 promoter. cholesteryl myristate bone morphogenetic protein 4 Rattus norvegicus
2 Cholesterol myristate significantly increases the expression of BMP4, BMPRIA, p-Smad1/5/8, Id1 and its antiapoptotic target gene Bcl-xL in PC12 cells treated in serum-free condition. Cholesterol bone morphogenetic protein 4 Rattus norvegicus