Title : Thymidine kinase 1 deficient cells show increased survival rate after UV-induced DNA damage.

Pub. Date : 2010 Jun

PMID : 20544518






4 Functional Relationships(s)
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1 Here we show that cells deficient for the thymidine salvage enzyme thymidine kinase 1 (TK1) are more resistant to UV-induced DNA damage than TK1 positive cells although they have thymidine triphosphate (dTTP) levels of only half the size of control cells. thymidine 5'-triphosphate thymidine kinase 1 Homo sapiens
2 Here we show that cells deficient for the thymidine salvage enzyme thymidine kinase 1 (TK1) are more resistant to UV-induced DNA damage than TK1 positive cells although they have thymidine triphosphate (dTTP) levels of only half the size of control cells. thymidine 5'-triphosphate thymidine kinase 1 Homo sapiens
3 Here we show that cells deficient for the thymidine salvage enzyme thymidine kinase 1 (TK1) are more resistant to UV-induced DNA damage than TK1 positive cells although they have thymidine triphosphate (dTTP) levels of only half the size of control cells. thymidine 5'-triphosphate thymidine kinase 1 Homo sapiens
4 Here we show that cells deficient for the thymidine salvage enzyme thymidine kinase 1 (TK1) are more resistant to UV-induced DNA damage than TK1 positive cells although they have thymidine triphosphate (dTTP) levels of only half the size of control cells. thymidine 5'-triphosphate thymidine kinase 1 Homo sapiens