Title : Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6).

Pub. Date : 2010 Jul 2

PMID : 20466003






5 Functional Relationships(s)
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1 Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6). Water adenylate cyclase 6 Mus musculus
2 Adenylyl cyclase (AC) type VI (AC6) is a calcium-inhibitable enzyme which produces cAMP upon stimulation. Calcium adenylate cyclase 6 Mus musculus
3 Adenylyl cyclase (AC) type VI (AC6) is a calcium-inhibitable enzyme which produces cAMP upon stimulation. Cyclic AMP adenylate cyclase 6 Mus musculus
4 Activities of AC evoked by forskolin or a selective agonist of the V2 vasopressin receptor were lower in the kidneys of AC6-null mice compared to those of wildtype mice. Colforsin adenylate cyclase 6 Mus musculus
5 Results of a metabolic cage assay and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) showed for the first time that AC6 plays a critical role in regulating water homeostasis. Water adenylate cyclase 6 Mus musculus