Title : Extraction of CEA from tumour tissue, foetal colon and patients' sera, and the effect of perchloric acid.

Pub. Date : 1978 Feb

PMID : 204321






10 Functional Relationships(s)
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1 The use of perchloric acid and water for the extraction of CEA from tumour and foetal tissues has been investigated. Perchloric Acid CEA cell adhesion molecule 3 Homo sapiens
2 The use of perchloric acid and water for the extraction of CEA from tumour and foetal tissues has been investigated. Water CEA cell adhesion molecule 3 Homo sapiens
3 In the case of tumour, lower recoveries of CEA were obtained from perchloric acid extracts than from aqueous extracts of the same tissue. Perchloric Acid CEA cell adhesion molecule 3 Homo sapiens
4 CEA has also been extracted with 3M KCl solution from insoluble perchloric acid residues of tumour homogenates and cancer patients" serum. Potassium Chloride CEA cell adhesion molecule 3 Homo sapiens
5 CEA has also been extracted with 3M KCl solution from insoluble perchloric acid residues of tumour homogenates and cancer patients" serum. Perchloric Acid CEA cell adhesion molecule 3 Homo sapiens
6 Whilst a large proportion of CEA activity recovered from tumour was associated with the perchloric acid residue, the corresponding amounts from serum were very small. Perchloric Acid CEA cell adhesion molecule 3 Homo sapiens
7 CEA elution volumes for each extract, obtained by assay of Sephadex G-200 column fractions, showed significant heterogeneity in molecular size. sephadex CEA cell adhesion molecule 3 Homo sapiens
8 The purified CEA pools also showed quantitative variations in the binding profiles on Con A-Sepharose. Sepharose CEA cell adhesion molecule 3 Homo sapiens
9 It has been shown that perchloric acid modifies the carbohydrate in CEA, thus altering its Con A-binding properties. Perchloric Acid CEA cell adhesion molecule 3 Homo sapiens
10 It has been shown that perchloric acid modifies the carbohydrate in CEA, thus altering its Con A-binding properties. Carbohydrates CEA cell adhesion molecule 3 Homo sapiens