Title : Selectivity of digitalis glycosides for isoforms of human Na,K-ATPase.

Pub. Date : 2010 Jun 18

PMID : 20388710






1 Functional Relationships(s)
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1 Binding affinities of the digitalis glycosides, digoxin, beta-methyl digoxin, and digitoxin show moderate but highly significant selectivity (up to 4-fold) for alpha2/alpha3 over alpha1 (K(D) alpha1 > alpha2 = alpha3). Digitoxin adrenoceptor alpha 1D Homo sapiens