Title : Cholinergic drugs reverse AF64A-induced impairment of passive avoidance learning in rats.

Pub. Date : 1991

PMID : 2027921






1 Functional Relationships(s)
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1 Learning was significantly impaired at 3.75 nmol AF64A, a dose at which significant reduction in acetylcholine level and choline acetyltransferase and acetylcholinesterase activity in the hippocampus was observed but changes in monoamine levels in the hippocampus, general behavior, or sensory sensitivity were not observed. ethylcholine aziridinium acetylcholinesterase Rattus norvegicus