Pub. Date : 2010 Feb 15
PMID : 20103533
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Introduction of Mfn1(T109A), a GTPase-deficient mutant form of Mfn1, into MARCH5-RNAi cells not only disrupted mitochondrial elongation, but also abolished the increase in SA-beta-Gal activity. | 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid | mitofusin 1 | Homo sapiens |
2 | Introduction of Mfn1(T109A), a GTPase-deficient mutant form of Mfn1, into MARCH5-RNAi cells not only disrupted mitochondrial elongation, but also abolished the increase in SA-beta-Gal activity. | 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid | mitofusin 1 | Homo sapiens |
3 | Moreover, the aberrant mitochondrial phenotypes in MARCH5-RNAi cells were reversed by ectopic expression of Drp1, but not by hFis1, and reversion of the mitochondria morphology in MARCH5-depleted cells was accompanied by a reduction in SA-beta-Gal activity. | 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid | membrane associated ring-CH-type finger 5 | Homo sapiens |
4 | Moreover, the aberrant mitochondrial phenotypes in MARCH5-RNAi cells were reversed by ectopic expression of Drp1, but not by hFis1, and reversion of the mitochondria morphology in MARCH5-depleted cells was accompanied by a reduction in SA-beta-Gal activity. | 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid | membrane associated ring-CH-type finger 5 | Homo sapiens |