Title : CtIP links DNA double-strand break sensing to resection.

Pub. Date : 2009 Dec 25

PMID : 20064462






1 Functional Relationships(s)
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1 We find that CtIP translocates to DSBs, a process dependent on the DSB sensor complex Mre11-Rad50-NBS1, the kinase activity of ATM, and a direct DNA-binding motif in CtIP, and then promotes DSB resection. dsbs RAD50 double strand break repair protein Homo sapiens