Title : Enteropathogenic Escherichia coli inhibits intestinal vitamin B1 (thiamin) uptake: studies with human-derived intestinal epithelial Caco-2 cells.

Pub. Date : 2009 Oct

PMID : 19628653






2 Functional Relationships(s)
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1 Kinetic parameters of both the nanomolar (mediated by THTR-2) and the micromolar (mediated by THTR-1) saturable thiamin uptake processes were affected by EPEC infection. Thiamine solute carrier family 19 member 2 Homo sapiens
2 These results demonstrate for the first time that EPEC infection of human intestinal epithelial cells leads to inhibition in thiamin uptake via effects on physiological and molecular parameters of hTHTR-1 and -2. Thiamine solute carrier family 19 member 2 Homo sapiens