Title : Oxidative stress-related proteins in a Conn's adenoma tissue. Relevance for aldosterone's prooxidative and proinflammatory activity.

Pub. Date : 2010 Jan

PMID : 19625761






1 Functional Relationships(s)
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1 MATERIALS AND METHODS: We assessed gene and protein expression of p22phox (RT-PCR and Western blot), NAD(P)H oxidase subunit essential for superoxide production and gene expression of transforming growth fator (TGF) beta, plasminogen activator inhibitor (PAI)-1, and heme oxygenase (HO)-1, effectors of OxSt (RT-PCR), in a Conn"s adenoma, removed from a patient with primary hyperaldosteronism. Superoxides cytochrome b-245 alpha chain Homo sapiens