Title : Fluticasone propionate reduces bacterial airway epithelial invasion.

Pub. Date : 2008 Nov

PMID : 18684852






3 Functional Relationships(s)
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1 Both express phosphorylcholine, an epitope that mediates their interaction with airway epithelial cells via the platelet-activating factor receptor (PAFR). Phosphorylcholine platelet activating factor receptor Homo sapiens
2 The present work studies the effects of fluticasone propionate on the expression of PAFR on human airway epithelial cells, the invasion of these cells by S. pneumoniae and H. influenzae, and the course of pneumococcal infection in vivo. Fluticasone platelet activating factor receptor Homo sapiens
3 Fluticasone propionate was found to reduce PAFR expression on the surface of the two cells types studied. Fluticasone platelet activating factor receptor Homo sapiens