Pub. Date : 2008 Aug 13
PMID : 18571832
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PELP1 (proline-, glutamic acid-, and leucine-rich protein-1) is a novel estrogen receptor (ER)-interacting protein that has been implicated to be important for mediation of both the genomic and nongenomic signaling of 17beta-estradiol (E2). | Estradiol | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 2 | PELP1 (proline-, glutamic acid-, and leucine-rich protein-1) is a novel estrogen receptor (ER)-interacting protein that has been implicated to be important for mediation of both the genomic and nongenomic signaling of 17beta-estradiol (E2). | Estradiol | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 3 | PELP1 contains ten nuclear receptor-interacting boxes (LXXLL motifs), which allow it to interact with ER and other nuclear hormone receptors, a zinc finger, a glutamic acid-rich domain, and two proline-rich domains. | Glutamic Acid | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 4 | PELP1 contains ten nuclear receptor-interacting boxes (LXXLL motifs), which allow it to interact with ER and other nuclear hormone receptors, a zinc finger, a glutamic acid-rich domain, and two proline-rich domains. | Proline | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 5 | The proline-rich regions contain several consensus PXXP motifs, which allow PELP1 to couple the ER with SH3 domain-containing kinase signaling proteins, such as Src and PI3K P85 regulatory subunit. | Proline | proline, glutamate and leucine rich protein 1 | Homo sapiens |