Title : Alveolar type II cells isolated after silica-induced lung injury in rats have increased surfactant protein A (SP-A) receptor activity.

Pub. Date : 1991 Mar

PMID : 1848086






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Alveolar type II cells isolated after silica-induced lung injury in rats have increased surfactant protein A (SP-A) receptor activity. Silicon Dioxide surfactant protein A1 Rattus norvegicus
2 Alveolar type II cells isolated after silica-induced lung injury in rats have increased surfactant protein A (SP-A) receptor activity. Silicon Dioxide surfactant protein A1 Rattus norvegicus
3 The maximum total binding of [125I]SP-A (internalized and surface-bound SP-A) to type II cells increased with time after silica instillation and, at 21 d, was 4-fold greater than that of type II cells isolated from saline-treated rats (272.8 +/- 42.5 and 65.4 +/- 9.8 ng/10(5) cells, respectively; P less than 0.05). Silicon Dioxide surfactant protein A1 Rattus norvegicus
4 The receptor affinity for SP-A was the same for type II cells isolated from silica- and saline-treated animals. Silicon Dioxide surfactant protein A1 Rattus norvegicus