Title : Normal acute behavioral responses to moderate/high dose ethanol in GABAA receptor alpha 4 subunit knockout mice.

Pub. Date : 2008 Jan

PMID : 18076749






3 Functional Relationships(s)
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1 BACKGROUND: gamma-Aminobutyric acid type A receptors (GABA(A)-Rs) have been implicated in mediating some of the behavioral effects of ethanol (EtOH), but the contribution of specific GABA(A)-R subunits is not yet fully understood. Ethanol gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus
2 BACKGROUND: gamma-Aminobutyric acid type A receptors (GABA(A)-Rs) have been implicated in mediating some of the behavioral effects of ethanol (EtOH), but the contribution of specific GABA(A)-R subunits is not yet fully understood. Ethanol gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus
3 We further suggest that these findings are complicated by the demonstrated compensatory alterations in synaptic GABA(A)-R EtOH sensitivity and function in alpha 4 knockout mice. Ethanol gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus