Pub. Date : 2007 Sep 1
PMID : 17804729
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Furthermore, recent studies have shown that differential compartmentalization of PELP1 could be crucial in modulating sensitivity to tamoxifen. | Tamoxifen | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 2 | In this study, we investigated the role of PELP1 in resveratrol-induced autophagy in lung cancer and salivary gland adenocarcinoma cell lines. | Resveratrol | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 3 | Confocal microscopic analysis showed that resveratrol induced PELP1 accumulation in autophagosomes with green fluorescent protein-LC3. | Resveratrol | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 4 | The intermediary molecule involved in PELP1 accumulation in resveratrol-induced autophagosomes is hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), a trafficking molecule that binds to PELP1. | Resveratrol | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 5 | The intermediary molecule involved in PELP1 accumulation in resveratrol-induced autophagosomes is hepatocyte growth factor-regulated tyrosine kinase substrate (HRS), a trafficking molecule that binds to PELP1. | Resveratrol | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 6 | These results identify PELP1 for the first time in autophagosomes, implying that both PELP1 and HRS reallocate to autophagosomes in response to resveratrol treatment, which might be important in the process of autophagy in the cancer cells. | Resveratrol | proline, glutamate and leucine rich protein 1 | Homo sapiens |
| 7 | These results identify PELP1 for the first time in autophagosomes, implying that both PELP1 and HRS reallocate to autophagosomes in response to resveratrol treatment, which might be important in the process of autophagy in the cancer cells. | Resveratrol | proline, glutamate and leucine rich protein 1 | Homo sapiens |