Pub. Date : 1991 Dec 25
PMID : 1761576
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Guanine nucleotide biosynthesis is regulated by the cellular p53 concentration. | Guanine Nucleotides | transformation related protein 53, pseudogene | Mus musculus |
| 2 | The reversal of the induction phenotype by these purine salvage precursors implicated the purine nucleotide biosynthetic pathway as the cellular target for the antiproliferative action of p53. | purine | transformation related protein 53, pseudogene | Mus musculus |
| 3 | The reversal of the induction phenotype by these purine salvage precursors implicated the purine nucleotide biosynthetic pathway as the cellular target for the antiproliferative action of p53. | Purine Nucleotides | transformation related protein 53, pseudogene | Mus musculus |
| 4 | Subsequent genetic and biochemical analyses identified a p53 induction-related purine pathway defect which was localized to the step of inosine 5"-monophosphate conversion to xanthosine 5"-monophosphate. | purine | transformation related protein 53, pseudogene | Mus musculus |
| 5 | Subsequent genetic and biochemical analyses identified a p53 induction-related purine pathway defect which was localized to the step of inosine 5"-monophosphate conversion to xanthosine 5"-monophosphate. | Inosine Monophosphate | transformation related protein 53, pseudogene | Mus musculus |
| 6 | Subsequent genetic and biochemical analyses identified a p53 induction-related purine pathway defect which was localized to the step of inosine 5"-monophosphate conversion to xanthosine 5"-monophosphate. | xanthosine monophosphate | transformation related protein 53, pseudogene | Mus musculus |
| 7 | These findings define p53 as a cellular regulator of the synthesis of GTP, a key regulatory nucleotide for many important cellular processes. | Guanosine Triphosphate | transformation related protein 53, pseudogene | Mus musculus |
| 8 | Moreover, observations of the growth behavior of p53-inducible cells suggest that by regulating the production of GTP, p53 can control cellular quiescence. | Guanosine Triphosphate | transformation related protein 53, pseudogene | Mus musculus |
| 9 | Moreover, observations of the growth behavior of p53-inducible cells suggest that by regulating the production of GTP, p53 can control cellular quiescence. | Guanosine Triphosphate | transformation related protein 53, pseudogene | Mus musculus |