Pub. Date : 2007 Aug
PMID : 17537984
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | DEX exposure in vitro decreased expression of glial cell line-derived neurotrophic factor (GDNF) and increased expression of bone morphogenetic protein-4 (BMP-4) and transforming growth factor-beta1 (TGF-beta1). | Dexamethasone | bone morphogenetic protein 4 | Rattus norvegicus |
2 | DEX exposure in vitro decreased expression of glial cell line-derived neurotrophic factor (GDNF) and increased expression of bone morphogenetic protein-4 (BMP-4) and transforming growth factor-beta1 (TGF-beta1). | Dexamethasone | bone morphogenetic protein 4 | Rattus norvegicus |
3 | However, in kidneys collected at E20.5 after in vivo exposure for 2 days, GDNF expression was increased and BMP-4 and TGF-beta1 expression decreased suggesting a biphasic response in gene expression to DEX exposure. | Dexamethasone | bone morphogenetic protein 4 | Rattus norvegicus |