Pub. Date : 1991 Dec 5
PMID : 1744113
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phorbol ester induces manganese-superoxide dismutase in tumor necrosis factor-resistant cells. | Phorbol Esters | superoxide dismutase 2 | Homo sapiens |
| 2 | The effects of phorbol ester (TPA) and other known stimulators such as tumor necrosis factor (TNF), interleukin-1, and lipopolysaccharide on induction of mRNA for manganese-superoxide dismutase (Mn-SOD) were investigated in various cell lines. | Phorbol Esters | superoxide dismutase 2 | Homo sapiens |
| 3 | The effects of phorbol ester (TPA) and other known stimulators such as tumor necrosis factor (TNF), interleukin-1, and lipopolysaccharide on induction of mRNA for manganese-superoxide dismutase (Mn-SOD) were investigated in various cell lines. | Tetradecanoylphorbol Acetate | superoxide dismutase 2 | Homo sapiens |
| 4 | TPA enhanced Mn-SOD mRNA expression in TNF-resistant cell lines including HeLa cells, in which the other reagents also induced expression of the gene, but did not affect TNF-sensitive cells, in which the other stimulators did not alter expression of the gene. | Tetradecanoylphorbol Acetate | superoxide dismutase 2 | Homo sapiens |
| 5 | HeLa cells which had been desensitized to TPA by pretreatment with TPA for 24 h expressed Mn-SOD mRNA at a slightly higher level than the cells without TPA treatment. | Tetradecanoylphorbol Acetate | superoxide dismutase 2 | Homo sapiens |
| 6 | HeLa cells which had been desensitized to TPA by pretreatment with TPA for 24 h expressed Mn-SOD mRNA at a slightly higher level than the cells without TPA treatment. | Tetradecanoylphorbol Acetate | superoxide dismutase 2 | Homo sapiens |
| 7 | HeLa cells which had been desensitized to TPA by pretreatment with TPA for 24 h expressed Mn-SOD mRNA at a slightly higher level than the cells without TPA treatment. | Tetradecanoylphorbol Acetate | superoxide dismutase 2 | Homo sapiens |
| 8 | TPA-pretreated cells stimulated with TNF, however, expressed Mn-SOD mRNA at about twice the level of TNF-stimulated, TPA-untreated cells. | Tetradecanoylphorbol Acetate | superoxide dismutase 2 | Homo sapiens |