Title : Paraoxonase-2 reduces oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation.

Pub. Date : 2007 Apr 17

PMID : 17404154






5 Functional Relationships(s)
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1 Here, we analyzed the ROS-reducing capability of paraoxonase-2 (PON2) in different vascular cells and its involvement in the endoplasmic reticulum stress pathway known as the unfolded protein response. Reactive Oxygen Species paraoxonase 2 Homo sapiens
2 Here, we analyzed the ROS-reducing capability of paraoxonase-2 (PON2) in different vascular cells and its involvement in the endoplasmic reticulum stress pathway known as the unfolded protein response. Reactive Oxygen Species paraoxonase 2 Homo sapiens
3 By determining intracellular ROS, we show that overexpression of PON2 markedly reduced ROS, whereas its knockdown increased ROS levels significantly. Reactive Oxygen Species paraoxonase 2 Homo sapiens
4 By determining intracellular ROS, we show that overexpression of PON2 markedly reduced ROS, whereas its knockdown increased ROS levels significantly. Reactive Oxygen Species paraoxonase 2 Homo sapiens
5 By determining intracellular ROS, we show that overexpression of PON2 markedly reduced ROS, whereas its knockdown increased ROS levels significantly. Reactive Oxygen Species paraoxonase 2 Homo sapiens