Title : Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form.

Pub. Date : 1990 May

PMID : 1691710






1 Functional Relationships(s)
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1 We propose that immunoprecipitation of p53 by PAb240 is diagnostic of mutation in both murine and human systems and suggest that the different point mutations which convert p53 from a recessive to a dominant oncogene exert a common conformational effect on the protein. pab240 transformation related protein 53, pseudogene Mus musculus