Title : Double-strand breaks trigger MRX- and Mec1-dependent, but Tel1-independent, checkpoint activation.

Pub. Date : 2006 Aug

PMID : 16879433






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Together with the Tel1 PI3 kinase, the Mre11/Rad50/Xrs2 (MRX) complex is involved in checkpoint activation in response to double-strand breaks (DSBs), a function also conserved in human cells by Mre11/Rad50/Nbs1 acting with ATM. dsbs RAD50 double strand break repair protein Homo sapiens
2 Together with the Tel1 PI3 kinase, the Mre11/Rad50/Xrs2 (MRX) complex is involved in checkpoint activation in response to double-strand breaks (DSBs), a function also conserved in human cells by Mre11/Rad50/Nbs1 acting with ATM. dsbs RAD50 double strand break repair protein Homo sapiens