Pub. Date : 2006 Jun 23
PMID : 16636053
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The HCCH zinc coordination site, which is conserved among primate lentivirus Vif proteins, does not correspond to any known class of zinc-binding motif. | alpha-hexachlorocyclohexane | Vif | Human immunodeficiency virus 1 |
| 2 | Mutations of His/Cys residues in the HCCH motif impair zinc coordination, Cul5 binding, and APOBEC3G degradation. | alpha-hexachlorocyclohexane | cullin 5 | Homo sapiens |
| 3 | Mutations of His/Cys residues in the HCCH motif impair zinc coordination, Cul5 binding, and APOBEC3G degradation. | alpha-hexachlorocyclohexane | apolipoprotein B mRNA editing enzyme catalytic subunit 3G | Homo sapiens |
| 4 | We propose that the HCCH zinc-binding motif facilitates Vif-Cul5 binding by playing a structural role in positioning hydrophobic residues for direct contact with Cul5. | alpha-hexachlorocyclohexane | Vif | Human immunodeficiency virus 1 |
| 5 | We propose that the HCCH zinc-binding motif facilitates Vif-Cul5 binding by playing a structural role in positioning hydrophobic residues for direct contact with Cul5. | alpha-hexachlorocyclohexane | cullin 5 | Homo sapiens |
| 6 | We propose that the HCCH zinc-binding motif facilitates Vif-Cul5 binding by playing a structural role in positioning hydrophobic residues for direct contact with Cul5. | alpha-hexachlorocyclohexane | cullin 5 | Homo sapiens |