Pub. Date : 2006 Feb 3
PMID : 16438501
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In a study of the solvent effect on the alpha-effect, second-order rate constants (kNu-) have been determined spectrophotometrically for reactions of a series of substituted phenyl acetates with butan-2,3-dione monoximate (Ox-, alpha-nucleophile) and p-chlorophenoxide (p-ClPhO-, reference nucleophile) in DMSO-H2O (DMSO = dimethyl sulfoxide) mixtures of varying compositions at 25.0 +/- 0.1 degrees C. The magnitude of the alpha-effect, kOx-/kp-ClPhO-, increases as the DMSO content in the medium increases up to 40-50 mol %, reaching 500, one of the largest alpha-effect values, and then decreases on further addition of DMSO, resulting in a bell-shaped alpha-effect profile regardless of the nature of the substrates. | Phenylacetates | NADPH oxidase 4 | Homo sapiens |
| 2 | In a study of the solvent effect on the alpha-effect, second-order rate constants (kNu-) have been determined spectrophotometrically for reactions of a series of substituted phenyl acetates with butan-2,3-dione monoximate (Ox-, alpha-nucleophile) and p-chlorophenoxide (p-ClPhO-, reference nucleophile) in DMSO-H2O (DMSO = dimethyl sulfoxide) mixtures of varying compositions at 25.0 +/- 0.1 degrees C. The magnitude of the alpha-effect, kOx-/kp-ClPhO-, increases as the DMSO content in the medium increases up to 40-50 mol %, reaching 500, one of the largest alpha-effect values, and then decreases on further addition of DMSO, resulting in a bell-shaped alpha-effect profile regardless of the nature of the substrates. | butan-2,3-dione monoximate | NADPH oxidase 4 | Homo sapiens |