Title : Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes.

Pub. Date : 2006 Aug 18

PMID : 16246485






1 Functional Relationships(s)
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1 The highest concentration of alpha-BHC significantly increased the number and area of glutathione S-transferase placental form (GST-P) positive foci, preneoplastic lesions in the liver, but its low dose, 0.05 ppm, caused significant reduction, showing a J-shape dose-response curve. alpha-hexachlorocyclohexane glutathione S-transferase pi 1 Rattus norvegicus