Title : S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.

Pub. Date : 2005 Oct

PMID : 16187975






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 UGT2B7 exhibited an apparent K(m) (72 microm) of the same order as the high-affinity human liver microsomal activity, which was inhibited by the UGT2B7 selective "probe" fluconazole. Fluconazole UDP glucuronosyltransferase family 2 member B7 Homo sapiens
2 UGT2B7 exhibited an apparent K(m) (72 microm) of the same order as the high-affinity human liver microsomal activity, which was inhibited by the UGT2B7 selective "probe" fluconazole. Fluconazole UDP glucuronosyltransferase family 2 member B7 Homo sapiens