Title : Zofenoprilat-glutathione mixed disulfide as a specific S-thiolating agent of bovine lens aldose reductase.

Pub. Date : 2005 Jul-Aug

PMID : 15998238






2 Functional Relationships(s)
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1 The ability of Zofenoprilat, an angiotensin-converting enzyme inhibitor carrying a thiol group, to intervene in protein S-thiolation processes was tested on bovine lens aldose reductase (ALR2). zofenoprilate lens aldose reductase pseudogene Bos taurus
2 Indeed, the S-thiolation of ALR2 by ZSSG occurred exclusively through the insertion of the Zofenoprilat moiety of ZSSG on the enzyme. zofenoprilate lens aldose reductase pseudogene Bos taurus