Title : Pigment epithelium-derived factor (PEDF) blocks angiotensin II signaling in endothelial cells via suppression of NADPH oxidase: a novel anti-oxidative mechanism of PEDF.

Pub. Date : 2005 Jun

PMID : 15846509






1 Functional Relationships(s)
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1 Antisense, but not sense, DNAs against p22phox, Nox4, or gp91phox/Nox2 were found significantly to inhibit Ang-II-induced ROS generation in HUVEC. Reactive Oxygen Species cytochrome b-245 alpha chain Homo sapiens