Pub. Date : 1992 Feb
PMID : 1573280
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [3H]dTTP incorporation in isolated nuclei was shown to be representative of replicative DNA synthesis by evidence that (i) incorporation was dependent on ATP and all four nucleoside precursors, (ii) incorporation was inhibited greater than 97% by aphidicolin, a specific inhibitor of DNA polymerase alpha and delta, and (iii) the DNase I-sensitive product banded in neutral CsCl at a density indicative of replicative DNA. | thymidine 5'-triphosphate | DNA polymerase alpha 1, catalytic subunit | Homo sapiens |