Pub. Date : 1992 Apr
PMID : 1565472
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we report that a high rate of mitosis and efficient dense focus formation in human embryonic lung fibroblasts (HEL cells) is induced by antisense oligonucleotide-directed inhibition of synthesis of p105-Rb, the product of the Rb-1 gene. | Oligonucleotides | RB transcriptional corepressor 1 | Homo sapiens |
| 2 | Here we report that a high rate of mitosis and efficient dense focus formation in human embryonic lung fibroblasts (HEL cells) is induced by antisense oligonucleotide-directed inhibition of synthesis of p105-Rb, the product of the Rb-1 gene. | Oligonucleotides | RB transcriptional corepressor 1 | Homo sapiens |
| 3 | mRNA specific for p105-Rb is truncated at the site of base pairing with the antisense oligonucleotide, and no synthesis of p105-Rb is observed. | Oligonucleotides | RB transcriptional corepressor 1 | Homo sapiens |