Title : An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China.

Pub. Date : 2005 May

PMID : 15615884






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 An association of UDP-glucuronosyltransferase 2B7 C802T (His268Tyr) polymorphism with bladder cancer in benzidine-exposed workers in China. benzidine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
2 UDP-Glucuronyltransferase 2B7 (UGT2B7) is involved in benzidine metabolism, as demonstrated by in vitro experiments with liver slices. benzidine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
3 UDP-Glucuronyltransferase 2B7 (UGT2B7) is involved in benzidine metabolism, as demonstrated by in vitro experiments with liver slices. benzidine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
4 To evaluate the possible association of UGT2B7 gene polymorphism with bladder cancer risk for benzidine-exposed subjects, diagnosed bladder cancer cases (n = 36) who were members of a cohort of benzidine-exposed workers in the Chinese dyestuff industry were investigated. benzidine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
5 This study points for the first time to an association between a homozygous mutant genotype of human UDP-glucuronosyltransferase 2B7 catalyzing the biotransformation of benzidine and an elevated bladder cancer risk for formerly benzidine-exposed workers of the dyestuff industry. benzidine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
6 This study points for the first time to an association between a homozygous mutant genotype of human UDP-glucuronosyltransferase 2B7 catalyzing the biotransformation of benzidine and an elevated bladder cancer risk for formerly benzidine-exposed workers of the dyestuff industry. benzidine UDP glucuronosyltransferase family 2 member B7 Homo sapiens