Title : Sertraline is metabolized by multiple cytochrome P450 enzymes, monoamine oxidases, and glucuronyl transferases in human: an in vitro study.

Pub. Date : 2005 Feb

PMID : 15547048






1 Functional Relationships(s)
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1 Sertraline N-carbamoyl glucuronidation was measured in human liver microsomes in bicarbonate buffer and under a CO2 atmosphere (K(m) = 50 microM) and was catalyzed at the fastest rate by recombinant human UGT2B7. Sertraline UDP glucuronosyltransferase family 2 member B7 Homo sapiens