Pub. Date : 1992 May 28
PMID : 1534660
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | As an inducer of P450 3A1/2, loratadine was slightly less effective than phenobarbital, and was considerably less effective than dexamethasone, which caused a 10- to 33-fold increase in testosterone 2 beta-, 6 beta- and 15 beta-hydroxylase activity. | Loratadine | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
| 2 | As an inducer of P450 3A1/2, loratadine was slightly less effective than phenobarbital, and was considerably less effective than dexamethasone, which caused a 10- to 33-fold increase in testosterone 2 beta-, 6 beta- and 15 beta-hydroxylase activity. | Dexamethasone | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |