Title : Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors.

Pub. Date : 2004 Jul 14

PMID : 15254090






1 Functional Relationships(s)
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1 These data indicate that BZ-resistant anxiety results from a developmental arrest of GABA(A)R expression in SW-R-/- mice, and a similar mechanism may be responsible for the BZ insensitivity of some anxiety patients. Benzodiazepines gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus