Title : C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils.

Pub. Date : 2004 Jun

PMID : 15078863






2 Functional Relationships(s)
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1 p22phox-based NAD(P)H oxidases exist in the vessel wall, acting as important superoxide-generating systems in the vasculature. Superoxides cytochrome b-245 alpha chain Homo sapiens
2 Because vascular p22phox is identical to neutrophil p22phox, we studied the association between the C242T, A640G, and -930A/G CYBA polymorphisms and the quantity of superoxide produced from neutrophils isolated from healthy adults to determine if these polymorphisms had any functional impact on NADPH oxidase function. Superoxides cytochrome b-245 alpha chain Homo sapiens