Pub. Date : 2004 Feb
PMID : 14751452
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Co-exposure to pyridostigmine bromide, DEET, and/or permethrin causes sensorimotor deficit and alterations in brain acetylcholinesterase activity. | Permethrin | acetylcholinesterase | Rattus norvegicus |
| 2 | Brainstem acetylcholinesterase (AChE) activity significantly increased following treatment with combinations of either DEET or permethrin at all doses, whereas the cerebellum showed a significant increase in AChE activity following treatment with a combination of PB/DEET/permethrin. | Permethrin | acetylcholinesterase | Rattus norvegicus |
| 3 | Brainstem acetylcholinesterase (AChE) activity significantly increased following treatment with combinations of either DEET or permethrin at all doses, whereas the cerebellum showed a significant increase in AChE activity following treatment with a combination of PB/DEET/permethrin. | Permethrin | acetylcholinesterase | Rattus norvegicus |
| 4 | Co-exposure to PB, DEET, and permethrin resulted in significant inhibition in AChE in midbrain. | Permethrin | acetylcholinesterase | Rattus norvegicus |
| 5 | PB alone or in combination with DEET and permethrin at all doses increased ligand binding for m2 muscarinic acetylcholine receptor in the cortex. | Permethrin | cholinergic receptor, muscarinic 2 | Rattus norvegicus |
| 6 | In addition, PB and DEET together or a combination of PB, DEET, and permethrin significantly increased ligand binding for nicotinic acetylcholine receptor. | Permethrin | cholinergic receptor nicotinic alpha 2 subunit | Rattus norvegicus |