Pub. Date : 1992 Dec 17
PMID : 1465135
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we report that tyrosine-phosphorylated Shc proteins form a specific complex with a non-phosphorylated 23K polypeptide encoded by the grb2/sem-5 gene. | Tyrosine | growth factor receptor bound protein 2 | Homo sapiens |
| 2 | These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. | Tyrosine | growth factor receptor bound protein 2 | Homo sapiens |
| 3 | These results suggest that Shc tyrosine phosphorylation can couple tyrosine kinases to Grb2/Sem-5, through formation of a Shc-Grb2/Sem-5 complex, and thereby regulate the mammalian Ras signalling pathway. | Tyrosine | growth factor receptor bound protein 2 | Homo sapiens |