Pub. Date : 1992 Oct
PMID : 1455421
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of chronic consumption of methylparathion on rat brain regional acetylcholinesterase activity and on levels of biogenic amines. | Methyl Parathion | acetylcholinesterase | Rattus norvegicus |
| 2 | A single dose of 1 mg MPTH/kg body weight in 15-day-old pups caused a significant decrease of acetylcholinesterase (AChE) activity in cerebellum (CE), motor cortex (MC) and brain stem (BS). | Methyl Parathion | acetylcholinesterase | Rattus norvegicus |
| 3 | A single dose of 1 mg MPTH/kg body weight in 15-day-old pups caused a significant decrease of acetylcholinesterase (AChE) activity in cerebellum (CE), motor cortex (MC) and brain stem (BS). | Methyl Parathion | acetylcholinesterase | Rattus norvegicus |
| 4 | A single dose of 0.2 mg MPTH/kg in 15 day old pups caused a reduction of AChE activity only in the BS, while a 0.1 mg MPTH/kg single dose given to 15-day-old pups caused no effect even in seven regions of the brain examined. | Methyl Parathion | acetylcholinesterase | Rattus norvegicus |
| 5 | Effect of low dose chronic administration of MPTH on AChE activity was also studied in CE, MC, BS, hippocampus (HI), striatum-accumbens (SA), spinal cord (SC) and also in the hypothalamus (HY). | Methyl Parathion | acetylcholinesterase | Rattus norvegicus |
| 6 | Administration of 0.1 mg MPTH/kg from second day to 15 days of age caused significant reduction of AChE activity in only 2 of the 7 brain regions studied. | Methyl Parathion | acetylcholinesterase | Rattus norvegicus |