Title : Mutation of the casein kinase II phosphorylation site abolishes the anti-proliferative activity of p53.

Pub. Date : 1992 Nov 11

PMID : 1454521






1 Functional Relationships(s)
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1 In order to understand the functional significance of phosphorylation by casein kinase II, we have introduced mutations at serine 386 in mouse p53, the residue phosphorylated by this kinase, and investigated their effects on the ability of p53 to arrest cell growth. Serine transformation related protein 53, pseudogene Mus musculus