Title : Platelet derived growth factor induces c-fos and c-myc mRNA in rat aortic smooth muscle cells in primary culture without elevation of intracellular Ca2+ concentration.

Pub. Date : 1992 Nov 16

PMID : 1445353






2 Functional Relationships(s)
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1 In the presence of 10 microM genistein and 1 mM NiCl2, PDGF induced c-fos and c-myc mRNA, although the [Ca2+]i elevation could be completely blocked by these two agents. Genistein Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 In the presence of 10 microM genistein and 1 mM NiCl2, PDGF induced c-fos and c-myc mRNA, although the [Ca2+]i elevation could be completely blocked by these two agents. Genistein MYC proto-oncogene, bHLH transcription factor Rattus norvegicus